The whole Freeze Dry Machine of freeze-dryer is actually a simultaneous process of heat and mass transfer (water vapor). The heat and mass transfer rates jointly affect the drying rate, thus affecting the whole freeze-drying cycle. All factors affecting the heat and mass transfer will affect the drying rate. Simple analysis is as follows:
1, the material form and composition
According to the morphology of freeze-dried materials, they are usually divided into solid and liquid. The shape of solid and the concentration of liquid have great influence on freeze drying rate.
4, drying indoor pressure
The pressure in the drying chamber affects the rate of heat and mass transfer. For mass transfer, the lower the pressure, the better, while for heat transfer, the higher the pressure, the better. The mass transfer rate is mainly determined by the temperature and pressure of the sublimation interface and the surface of the drying layer. To increase the escape rate of water vapor in the drying layer, one is to increase the temperature of the sublimation interface so as to increase the water vapor pressure at the interface. The second is to improve the vacuum degree of the drying chamber and reduce the vapor pressure on the surface of the drying layer.
5, heat transfer mode heat transfer mode
According to the traditional classification, it can be divided into conduction, convection, heat radiation and medium heating (microwave heating). The sublimation drying process involves the transfer of heat and mass (water vapor), therefore, the way of heat transfer to transfer heat to materials more effectively has a greater impact on the drying rate.
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